We report on numerical self-consistent field (SCF) calculations on the single-chain conformation of an electrostatically charged, yet poorly soluble, flexible polymer. We find numerical evidence that a “necklace of beads” conformation is self-organized and speculate that the predicted cascade of conformational transitions can be probed via a single-chain mechanical experiment with an atomic force microscope.
No takes yet. Share an insight, caveat, or question.
Pickett et al. (2001) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: