The chiral bicyclic guanidinium compound (2b) binds oxoanionic guests by a unique ion pairing pattern, which is confirmed by the X-ray crystal structure of the nitrate salt (2S, 8S)-2,8-bis(t-butyldiphenylsilyloxymethyl)-3,4,6,7,8,9-hexahydro-2H-pyrimido[1,2a]pyrimidine hydronitrate, and allows enantiodifferentiation of racemic carboxylic acids by NMR.
No takes yet. Share an insight, caveat, or question.
Gleich et al. (1990) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: