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In his Perspective, [Du Pasquier][1] discusses findings of [ Watson et al. ][2] that alternate splicing of the locus encoding the insect homolog of the Down syndrome cell adhesion molecule generates a vast diversity of immunoglobulin superfamily receptors used in the nervous system and in the immune system. Du Pasquier discusses the implications of this situation for the regulation and the evolution of this locus. [1]: http://www.sciencemag.org/cgi/content/full/309/5742/1826 [2]: http://www.sciencemag.org/cgi/content/short/309/5742/1874
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Louis Du Pasquier (2005) studied this question.
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