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January 1, 1995Journal of Antimicrobial Chemotherapy

Potent activity of meropenem against Escherichia coli arising from its simultaneous binding to penicillin-binding proteins 2 and 3

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Authors

YSYoshihiro SumitaSumitomo Dainippon Pharma (Japan)MFMasatomo Fakasawa

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Sumita et al. (1995) studied this question.

synapsesocial.com/papers/6a9375dd92ea9fef16651cd6https://doi.org/10.1093/jac/36.1.53
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of two carbapenems, SM-7338 and imipenem. Affinities for penicillin-binding proteins and morphological changes.1990 · 79 citations
  2. 2Diffusion of meropenem and imipenem through the outer membrane of Escherichia coli K-12 and correlation with their antibacterial activities1992 · 33 citations
  3. 3Synergistic effect of cephalexin with mecillinam.1981 · 20 citations
  4. 4Domains involved in osmoregulation of the ompF gene in Escherichia coli1985 · 24 citations
  5. 5Decreased outer membrane permeability in imipenem-resistant mutants of Pseudomonas aeruginosa1989 · 107 citations