Boronic Acid-Based Electrochemical Sensors for Detection of Biomolecules

Boronic acids can form reversible covalent bonds with 1, 2- or 1, 3-diols to generate five or six-membered cyclic complexes. Thus, boronic acid functionalized compounds and materials have attracted much attention in both chemistry and biology as the recognition motif for chemo/biosensing and enrichment and separation of biomolecules. In this contribution, we addressed the recent progress of boronic acid-based electrochemical sensors for the detection and immobilization of diol-containing biomolecules including dopamine and glycoproteins. This work will be valuable for the development of novel boronic acid-based electrochemical sensors.