What question did this study set out to answer?

Investigate the conformational properties and secondary structures of cross-linked polystyrene resin-bound oligoleucine peptides in the swollen state using infrared spectroscopy.

October 1, 1984Macromolecules

Syntheses and properties of resin-bound oligopeptides. 2. Infrared spectroscopic conformational analysis of cross-linked polystyrene resin bound oligoleucines in the swollen state

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MNMitsuaki NaritaNihon Pharmaceutical University YTYasuko TomotakeMitsubishi Group (Japan)SIShizuko IsokawaDr Emilio B Espinosa Sr Memorial State College of Agriculture and Technology

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Implication

Experimental study demonstrates infrared conformational changes of cross-linked polystyrene-bound oligoleucines in the swollen state, highlighting peptide structural behavior during solid-phase...

Key Points

Investigate the conformational properties and secondary structures of cross-linked polystyrene resin-bound oligoleucine peptides in the swollen state using infrared spectroscopy.
Synthesized series of oligoleucine peptides covalently anchored to cross-linked polystyrene supports.
Conducted infrared spectroscopic conformational measurements on the resin-supported peptide chains while swollen in organic solvents.
Infrared absorption bands identified distinct secondary conformational structures adopted by the resin-bound oligoleucine sequences in the swollen state.
Conformational transitions and aggregation tendencies depended directly on oligoleucine chain length and polymer solvation environment.

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Narita et al. (1984) studied this question.

synapsesocial.com/papers/6a93769330aeca7d13d3b08d https://doi.org/10.1021/ma00140a004

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Implication

Experimental study demonstrates infrared conformational changes of cross-linked polystyrene-bound oligoleucines in the swollen state, highlighting peptide structural behavior during solid-phase...

Syntheses and properties of resin-bound oligopeptides. 2. Infrared spectroscopic conformational analysis of cross-linked polystyrene resin bound oligoleucines in the swollen state

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Implication

Key Points

Cite This Study

Syntheses and properties of resin-bound oligopeptides. 2. Infrared spectroscopic conformational analysis of cross-linked polystyrene resin bound oligoleucines in the swollen state

Discussion

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Implication

Key Points

Cite This Study

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