Enantioselective fluorinations made easier! Chiral N-fluoroammonium salts such as A, or chiral catalysts generated from complexes B (L=ligand) broaden the substrate scope for electrophilic fluorination. Starting from prochiral substrates they offer an efficient approach to chiral fluoro derivatives such as C. Additionally, fluorinated stereogenic centers can be generated from nucleophilic, catalytic epoxide opening.
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Kilian Muñiz (2001) studied this question.
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