A simple, efficient and environmentally friendly procedure has been developed for the reaction of Meldrum’s acid with salicylaldehydes. 3-Carboxycoumarins 5 were synthesised in high yields (78–96%) and excellent selectivities (95–98%) by carrying out the reaction in water at reflux for 10 h, avoiding the addition of any catalyst.
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Maggi et al. (2001) studied this question.
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