Answers are grounded in this paper and cite their sources.
Double asymmetric reaction of chiral ( Z )-(γ-chloroallyl)borane, 2, with α-chiral aldehydes ( 3 − 7 ) provide a new practical method for the generation of 2,3-syn-3,4-anti and 2,3-syn-3,4-syn chiral vinylchlorohydrins ( 8 − 17 ) and vinyl epoxides ( 18 − 27 ). Both enantiomers of 2 exhibited excellent diatereoselectivity (≥90 de) for matched cases. The mismatched cases yielded moderate to good diastereoselectivity.
No takes yet. Share an insight, caveat, or question.
Hu et al. (1998) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: