Methyl crepenynate (methyl‐cis‐9‐octadecen‐12‐ynoate) is readily isomerized by potassium hydroxide in ethylene glycol to an 8,10,12‐octadecatrienoic acid in good yield. A reaction carried out at 120C for 1 hr in 10% base is sufficient to convert the nonconjugated enyne system completely to conjugated triene systems.
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Mikolajczak et al. (1965) studied this question.
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