Hyperoside: a review of pharmacological effects

Hyperoside, also known as quercetin-3-O-β-D-galactopyranoside, belongs to the class of flavonol glycosides. Its aglycon is quercetin, and the sugar base is galactopyranoside. It is made of quercetin. The O atom at the 3 rd position of the element is connected to the sugar group by a β-glycosidic bond. Hyperoside, which is widely present in the planted objects, such as the fruits and whole plants of Hypericaceae, Rosaceae , Campanulaceae , Lamiaceae , and Berberis spp., has received extensive attention due to its anti-inflammation, anti-oxidation, anti-tumor, and other disease activities, as well as its protective effects on the cardiovascular system, nervous system, digestive system and immune system. While glycosides are a commonly researched topic, there are very few studies on the metabolic pathways, and its overuse and adverse reactions are rarely reported. This article provides a comprehensive review of the pharmacological research results of hyperoside, and a new perspective on the limitations of the existing research on metabolic pathways and toxicology. It provides new ideas for further research and clinical application of hyperoside.