The substance produced by certain bacteria from ℓ-tryptophane and which possesses v+ hormone activity in Drosophila has been found to be a sucrose ester of ℓ-kynurenine. The ℓ-kynurenine is the essential active portion of the molecule. ℓ-Kynurenine, ℓ-kynurenine sulfate, and the ℓ-kynurenine-sucrose derivative have the same molar activity when tested in Drosophila larvae. This value approximates 12 X 10^6 units per mM.
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Tatum et al. (1941) studied this question.
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