tert-Butyl hypochlorite/HNa faujasite X in acetonitrile represents an efficient and highly regioselective system for mono-chlorination of a wide range of mono- and di-substituted aromatic substrates in mild conditions. Partially protonated faujasite X is far superior to amorphous silicas and to other zeolites in terms of efficiency and regioselectivity. Advantages of tert-butyl hypochlorite over other chlorinating reagents have been demonstrated. The method is suitable for large scale work.
No takes yet. Share an insight, caveat, or question.
Smith et al. (1999) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: