NMR Spectroscopy with Spectral Editing for the Analysis of Complex Mixtures

C hemical analysis of complex mixtures is of increasing importance in the ® elds of environm ental chem istr y, petroleum chemistry, biochemistry, and m aterials chemistry.Many times the analyte is present in a com plex m atrix such as blood, plasma, or oil.Alternatively, the compounds of interest may themselves constitute a complex mixture.Simpli® cation is the m ain objective of most investigators when faced with complex m ixture analysis.Such simpli® cation can often be achieved by the separation of the mixture into its individual components by chrom atographic or electrophoretic m eans.These simpler components can then be analyzed individually to gain inform ation about the system as a whole.However, it is frequently necessar y or desirable to study the m ixture intact without effecting a separation.Therefore, the