Key result
Transoesophageal echocardiography under light sedation caused mean arterial oxygen saturation to fall from 95.4% to 90.7% (P<0.001), with 18% of patients developing significant hypoxaemia.
Why the study?
Does transoesophageal echocardiography under light intravenous sedation cause arterial oxygen desaturation in referred patients?
Observational (n=150)
No
Does transoesophageal echocardiography under light intravenous sedation cause arterial oxygen desaturation in referred patients?
Absolute Event Rate: 90.7% vs 95.4%
p-value: p=<0.001
Transoesophageal echocardiography under light sedation frequently causes arterial oxygen desaturation, highlighting the need for routine transcutaneous oximetry and supplementary oxygen availability.
OBJECTIVES: To establish the incidence and severity of arterial oxygen desaturation during transoesophageal echocardiography performed under light intravenous sedation; to determine which patients are at greatest risk; and to assess the effects of supplementary oxygen treatment. DESIGN: Prospective study of 150 patients referred for transoesophageal echocardiography. SETTING: Echocardiography laboratory in a tertiary cardiothoracic referral centre. MAIN OUTCOME MEASURE: Transcutaneous arterial oxygen saturation. RESULTS: During transoesophageal echocardiography mean (SD) arterial oxygen saturation (SaO2) fell in 144 of 150 patients (96%) from 95.4%(2.6%) to 90.7%(6.3%) (p < 0.001). Significant hypoxaemia, defined as SaO2 < 90%, was found in 27 of 150 patients (18%); in this group SaO2 fell from 92.9%(3.5%) to 81.8%(9.6%) (p < 0.001), but rose rapidly on oxygen to 95.5%(2.4%) (p < 0.001). Two patients became profoundly hypoxaemic with SaO2 values of 35% and 74%. The principal risk factors for hypoxaemia during transoesophageal echocardiography were mitral valve disease, severe mitral regurgitation, and New York Heart Association symptomatic class III or IV. CONCLUSIONS: Transcutaneous oximetry and supplementary oxygen should be available routinely during transoesophageal echocardiography.
No takes yet. Share an insight, caveat, or question.
Scriven et al. (1994) conducted an observational in Patients referred for transoesophageal echocardiography (n=150). Transoesophageal echocardiography under light intravenous sedation vs. Baseline was evaluated on Transcutaneous arterial oxygen saturation (p=<0.001). Transoesophageal echocardiography under light sedation caused mean arterial oxygen saturation to fall from 95.4% to 90.7% (P<0.001), with 18% of patients developing significant hypoxaemia.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: