Key result
Spontaneous subarachnoid haemorrhage was associated with higher tissue Doppler indices of left ventricular contractility compared to healthy controls during the acute phase (p<0.001).
Why the study?
Does the acute phase of subarachnoid haemorrhage alter left ventricular myocardial function compared to healthy controls?
Case-Control (n=36)
Does the acute phase of subarachnoid haemorrhage alter left ventricular myocardial function compared to healthy controls?
p-value: p=<0.001
Patients in the acute phase of subarachnoid hemorrhage exhibit increased systolic and diastolic function on tissue Doppler echocardiography, indicative of a hyperdynamic and hypervolemic circulation.
Suggests hyperdynamic LV response in acute SAH; hypothesis-generating for neurocardiogenic effects, needs prospective validation.
OBJECTIVES: Previous reports suggest that left myocardial ventricular function changes during the course of a subarachnoid haemorrhage. The aim of this study was to evaluate left myocardial ventricular function with tissue Doppler echocardiography at two time points during the acute phase of a subarachnoid haemorrhage. DESIGN: Eighteen consecutive patients (median 52 years, range 33-74) with spontaneous subarachnoid haemorrhage and no history of heart disease were examined at 1-5 days and at 6-11 days following ictus. Eighteen control subjects were included for comparison (52 years, 32-72). RESULTS: Tissue Doppler indices of left ventricular contractility were higher in patients than in controls at both examinations (p<0.001). Indices of left ventricular stroke volume were elevated compared to controls at examination 1 (p<0.05), but not at examination 2. Early diastolic relaxation rate decreased from examination 1 to 2 (p=0.001). Three patients had increased troponin T (range 0.010-0.131 microg/l). CONCLUSION: In patients with subarachnoid haemorrhage, systolic and diastolic function is increased compared to healthy controls, suggesting a hyperdynamic and hypervolemic circulation.
No takes yet. Share an insight, caveat, or question.
Sandvei et al. (2008) conducted a case-control in Spontaneous subarachnoid haemorrhage (n=36). Spontaneous subarachnoid haemorrhage vs. Healthy controls was evaluated on Tissue Doppler indices of left ventricular contractility (p=<0.001). Spontaneous subarachnoid haemorrhage was associated with higher tissue Doppler indices of left ventricular contractility compared to healthy controls during the acute phase (p<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: