Key result
Chick interferon consists of several active components with different electric charges that are separable by pH, although most of the interferon is isoelectric near neutrality.
Demonstrates that chick interferon consists of multiple active components with different electric charges, though mostly isoelectric near neutrality.
Multiple charge variants may affect chick interferon assay standardization; leaves open mammalian isoform relevance.
Chick interferon from allantoic fluid, virus-induced and partly purified, consists of several active components of different charge. The components are separable by elution at different pH values from a carboxymethyl-Sephadex column; they also occupy different pH zones in electrofocusing gradients. Most of the interferon is, however, isoelectric near neutrality.
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K. H. Fantes (1969) studied this question. Chick interferon consists of several active components with different electric charges that are separable by pH, although most of the interferon is isoelectric near neutrality.
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