Somatuline Autogel provides effective control of growth hormone levels and is at least as effective as intramuscular Somatuline LA. Somatuline Autogel has a first order kinetic profile providing at least 28 days' efficacy with reduced burst release and a more consistent drug release over the dose period. The product is presented in a pre-filled syringe and is given deep subcutaneously.
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Stafford L. Lightman (2002) studied this question.
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