Electron Microscope Study on the Hemangiomas in Poems Syndrome

We examined by light and electron microscopy the cutaneous hemangiomas of the POEMS syndrome (1, 2). The reddish papules showed histologic features of a lobulated cellular capillary hemangioma and overlapping features of a pyogenic granuloma and a cherry angioma. Interesting findings of these angiomas were 1) the intravascular endothelial proliferation not in the preexisting large vessels but in the capillaries composing the tumor and 2) the presence of particles resembling Epstein‐Barr virus and fine filamentous structures in the cytoplasma of the intravascular cells.