Why the study?
Polypharmacy is common in patients with AF, but little is known about how prescribed drug patterns affect management and prognosis.
Do different pharmacological treatment patterns affect the risk of all-cause death and MACE in patients with atrial fibrillation?
Observational (n=21,245)
Yes
Do different pharmacological treatment patterns affect the risk of all-cause death and MACE in patients with atrial fibrillation?
In patients with atrial fibrillation, distinct pharmacological treatment patterns (such as Heart Failure, Mixed Morbidity, and High Medicated) are associated with higher risks of mortality and MACE compared to a low medicated pattern.
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Corica et al. (2025) conducted an observational in Atrial Fibrillation (n=21,245). Heart Failure, Mixed Morbidity, and High Medicated treatment patterns vs. Low Medicated treatment pattern was evaluated on Composite of all-cause death and MACE (HR 1.32, 95% CI 1.14-1.53, p=<0.001).
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