Why the study?
Does intraperitoneal infiltration of bupivacaine reduce pain score and total analgesic requirement in patients undergoing gynaecological laparoscopic surgery?
RCT (n=250)
Double-blind
Lottery method followed by systematic randomized allocation
Yes
Does intraperitoneal infiltration of bupivacaine reduce pain score and total analgesic requirement in patients undergoing gynaecological laparoscopic surgery?
Absolute Event Rate: 3.67% vs 5.57%
p-value: p=0.001
This is the authors' abstract. We don't add key points for this paper.
Postoperative management of pain has always been challenging as more and more patients are undergoing minimal invasive surgery with patients discharged on day care basis. The objective of the study is to evaluate the effect of intraperitoneal infiltration of Bupivacaine over pain score and total analgesic requirement in patients undergoing gynaecological laparoscopic surgery.
Reduces systemic analgesic needs after laparoscopic gynaecological surgery; extends RCT evidence for intraperitoneal local anesthetics in minimally invasive procedures.
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Patel et al. (2018) conducted an RCT in Postoperative pain in laparoscopic gynaecological surgery (n=250). Intraperitoneal Bupivacaine vs. 30 mL of normal saline was evaluated on Visual Analogue Score (VAS) for pain at 24 hours (p=0.001).
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