Key result
Matrix metalloproteinases, prostaglandins, and endothelins regulate implantation, where abnormal trophoblast invasion may lead to miscarriage, placental abruption, or deep placental adherence.
IntroductionThe development of the hemochorial placenta in humans involves apposition and attachment of the blastocyst to the uterine wall, penetration of the epithelium and invasion through the decidua to the superficial layers of the myometrium. Implantation is a crucial process for the establishment of a normal pregnancy. Excessive invasion of the trophoblast may lead to adherence of the placenta deep in the myometrium. Inadequate trophoblast invasion may be implicated in the pathophysiology of miscarriage or placental abruption.
No takes yet. Share an insight, caveat, or question.
A 1998 study conducted a review in Pregnancy complications (miscarriage, placental abruption). Matrix metalloproteinases, prostaglandins and endothelins was evaluated. Matrix metalloproteinases, prostaglandins, and endothelins regulate implantation, where abnormal trophoblast invasion may lead to miscarriage, placental abruption, or deep placental adherence.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: