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December 13, 2002Proceedings of the National Academy of Sciences

A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling

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Authors

HKHelena KarlströmKarolinska InstitutetPBPaul BeatusThe University of QueenslandKDKarin DannaeusUppsala University Hospital

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Karlström et al. (2002) studied this question.

synapsesocial.com/papers/6a93a25173075f1cdcafd4e4https://doi.org/10.1073/pnas.252624099
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Notch1 receptor is cleaved constitutively by a furin-like convertase1998 · 743 citations
  2. 2Intracellular Cleavage of Notch Leads to a Heterodimeric Receptor on the Plasma Membrane1997 · 617 citations