The administration of zinc supplements in pharmacological doses without knowledge of tissue zinc status carries risks, as this impairs absorption and may precipitate deficiency of other trace elements, particularly iron4 and copper.5We therefore suggest that tissue zinc depletion should be established before zinc supplementation and that the trace element profile is monitored during such treatment.
No takes yet. Share an insight, caveat, or question.
M G Jacoby (1982) studied this question.