A spectrophotometric method is described for the quantitative determination of the quaternary ammonium compound, poldine methyl methosulphate in aqueous solution and in biological fluids. The method involves coupling with methyl orange with simultaneous extraction into a mixture of ethylene dichloride and isopentanol and the determination of the optical density of the resulting acidified solution. The effect of pH on the coupling and extraction and the specificity of the reaction towards related compounds are examined.
No takes yet. Share an insight, caveat, or question.
Langley et al. (1963) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: