Key result
MitraClip implantation successfully treated severe dynamic functional mitral regurgitation in a patient with heart failure, resulting in trivial residual regurgitation and improvement to NYHA class I at 8 months.
Case Report (n=1)
No
MitraClip implantation represents a viable therapeutic option for heart failure patients suffering from dynamic functional mitral regurgitation despite optimized medical therapy.
Functional mitral regurgitation (FMR) is frequent in patients with heart failure (HF). It develops as a consequence of left ventricle (LV) geometry alterations, causing imbalance between increased tethering forces and decreased closing forces exerted on the mitral valve apparatus during systole.FMR is known to change at rest and during effort, due to preload-afterload changes, myocardial ischemia, and/or LV dysfunction. Despite optimized medical therapy, an FMR can be responsible of shortness of breath limiting quality of life and decompensation. In this report, we present a case of dynamic FMR treated with MitraClip.MitraClip implantation is a successful and innovative opportunity for HF patients with FMR.
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Duino et al. (2015) conducted a case report in Dynamic functional mitral regurgitation and heart failure (n=1). MitraClip was evaluated on Reduction in mitral regurgitation and improvement in functional status. MitraClip implantation successfully treated severe dynamic functional mitral regurgitation in a patient with heart failure, resulting in trivial residual regurgitation and improvement to NYHA class I at 8 months.
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