A clinical trial is monitored for efficacy or safety; the variable of interest is death or a similarly serious event. The probability that one therapy has a greater mortality rate than the other is calculated ad libitum during the trial. Adjustments are made for differing patients' prognoses and for survival times.
No takes yet. Share an insight, caveat, or question.
D. A. Berry (1989) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: