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The sex distribution of Australia antigen was determined in ten disease groups and 13 presumed normal populations tested in our laboratory. In 22 of these 23 independent studies, the frequency of Australia antigen was higher in males than in females (P<.001). The increased frequency in males was most marked in the lower age groups (less than 20 years). The overall ratio of Australia antigen in males to females is 1.58.
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Baruch S. Blumberg (1972) studied this question.
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