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April 13, 2021Acta Biochimica PolonicaOpen Access

Evidence of independent introductions of RHDV2 strains in Poland based on the genome analysis of viral isolates from 2016–2018

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Key result

Phylogenetic characterization of RHDV2 strains detected in Poland between 2016-2018 confirms that strains from 2018 and 2016-2017 were introduced independently.

Why the study?

The study was conducted to investigate the molecular epidemiology of independently introduced RHDV2 strains in Poland.

Population

RHDV2 and RHDVa strains from domestic and wild rabbits in Poland

Comparison

RHDV2 strains from 2018 and RHDVa from 2015 vs native RHDV2 strains from 2016-2017 and reference sequences

Design

Molecular epidemiological and phylogenetic genome analysis

Authors

AFA. FitznerAKA. KęsyKBKrzysztof Bulenger

Discussion

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Member takes

Overview

Supports targeted RHDV2 surveillance in lagomorphs; leaves open introduction sources and dynamics.

PICO

P
Population
RHDV2 infection in rabbits
E
Exposure / Comparator
Genome analysis of RHDV2 strains vs Reference sequences and older strains
O
Primary Outcome
Nucleotide sequence similarity and phylogenetic clustering

Cite This Study

Fitzner et al. (2021) studied RHDV2 infection in rabbits. Genome analysis of RHDV2 strains vs. Reference sequences and older strains was evaluated on Nucleotide sequence similarity and phylogenetic clustering. Phylogenetic characterization of RHDV2 strains detected in Poland between 2016-2018 confirms that strains from 2018 and 2016-2017 were introduced independently.

synapsesocial.com/papers/6a93b5f673075f1cdcafdde1https://doi.org/10.18388/abp.2020_5547
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Spillover Events of Infection of Brown Hares (<i>Lepus europaeus</i>) with Rabbit Haemorrhagic Disease Type 2 Virus (RHDV2) Caused Sporadic Cases of an European Brown Hare Syndrome-Like Disease in Italy and Spain2016 · 115 citations
  2. 2Detection of rabbit haemorrhagic disease virus 2 (GI.2) in Poland2018 · 18 citations