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June 21, 2006Blood

Hypogammaglobulinemia and exacerbated CD8 T-cell–mediated immunopathology in SAP-deficient mice with chronic LCMV infection mimics human XLP disease

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Authors

SCShane CrottyThe Wistar InstituteMMMegan McCauslandThe Wistar InstituteRARachael D. AubertCenters for Disease Control and Prevention

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Crotty et al. (2006) studied this question.

synapsesocial.com/papers/6a93ba7d744b618ad237eaa5https://doi.org/10.1182/blood-2006-04-018929
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  5. 5Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product2005 · 349 citations