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Escherichia coli has two known modes for termination of RNA transcription(1, 2, 3, 4). One is intrinsic to the function of RNA polymerase, which can spontaneously terminate transcription in response to certain, limited sequences. The other mode is dependent upon the action of an essential protein factor called Rho and occurs at sequences that are specific for its function but that are less constrained than the sequences for intrinsic termination.
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John P. Richardson (1996) studied this question.
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