The metabolites, (24S)-3β-acetoxyergost-5-en-21-oic acid (2), 5′-O-acetylthymidine (3), 3′-O-acetylthymidine (4), and p-vinylbenzyl alcohol (5), along with a known steroid (1) were isolated from the EtOAc extract of the Formosan soft coral Caldiella australis. The structures of new metabolites were determined on the basis of spectroscopic (including 1D and 2D NMR) analyses and by comparison of their NMR spectral data with those of related compounds. Except for 3, all compounds exhibited cytotoxic activity of various degrees of potency against a limited panel of human liver and breast cancer cell lines.
No takes yet. Share an insight, caveat, or question.
Ahmed et al. (2006) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: