Treatment of Acanthosis Nigricans of the Axillae Using a Long-Pulsed (5-msec) Alexandrite Laser

BACKGROUND: Acanthosis nigricans of the axillae is a common cutaneous disorder that is difficult to treat. OBJECTIVE: The objective was to assess the efficacy and safety of a long-pulsed alexandrite laser (5 msec) in the treatment of acanthosis nigricans of the axillae. METHODS: A single axilla was treated using the long-pulsed alexandrite laser. Ten sessions were required, at fluences of 16 to 23 J/cm2 using either 10- or 12.5-mm spot sizes. The untreated axilla served as a control. RESULTS: Greater than 95% clearance was achieved after seven sessions. There was no recurrence after 2 years. The untreated axilla was unchanged. CONCLUSIONS: The long-pulsed alexandrite laser can effectively and safely treat acanthosis nigricans of the axillae.