Key result
Cardiac surgery during pregnancy resulted in 92.7% maternal survival and 56.0% healthy live births, with emergency surgery significantly correlating with worse maternal prognosis (P<0.001).
Why the study?
What are the maternal and fetal outcomes and prognostic factors associated with cardiac surgery performed during pregnancy and puerperium?
Observational (n=41)
What are the maternal and fetal outcomes and prognostic factors associated with cardiac surgery performed during pregnancy and puerperium?
Cardiac surgery during pregnancy allows for high maternal survival but carries significant fetal risks, with emergency surgery being a strong predictor of worse maternal outcomes.
Answers are grounded in this paper and cite their sources.
Supports individualized decisions for cardiac surgery in pregnancy; Level 5 data leave open prospective validation of timing and fetal risks.
BACKGROUND: Cardiac surgery improves the maternal prognosis in cases refractory to medical therapy. However, it is associated with risks to the fetus when performed during pregnancy. OBJECTIVE: To analyze maternal-fetal outcome and prognosis related to cardiac surgery performed during pregnancy and puerperium. METHODS: The outcome of 41 gestations of women undergoing cardiac surgery during pregnancy and puerperium was studied. Fetal cardiotocography was performed throughout the procedure in patients with gestational age above 20 weeks. RESULTS: Mean maternal age was 27.8 +/- 7.6 years; there was a predominance of patients with rheumatic valve disease (87.8%), of whom 15 (41.6%) underwent reoperation due to prosthetic valve dysfunction. Mean extracorporeal circulation time was 87.4+/- 43.6 min and hypothermia was used in 27 (67.5%) cases. Thirteen (31.7%) mothers experienced no events and gave birth to live healthy newborns. Postoperative outcome of the remaining 28 (68.3%) pregnancies showed: 17 (41.5%) maternal complications and three (7.3%) deaths; 12 (29.2%) fetal losses, and four (10%) cases of neurological malformation, two of which progressed to late death. One patient was lost to follow-up after surgery. Nine (21.9%) patients underwent emergency surgery, and this variable was correlated with maternal prognosis (p<0.001) CONCLUSION: Cardiac surgery during pregnancy allowed survival of 92.7% of the mothers, and 56.0% of the patients who presented cardiac complications refractory to medical therapy gave birth to healthy children. Worse maternal prognosis was correlated with emergency surgery.
No takes yet. Share an insight, caveat, or question.
Ávila et al. (2009) conducted an observational in Cardiac complications refractory to medical therapy during pregnancy (n=41). Cardiac surgery was evaluated on Maternal survival. Cardiac surgery during pregnancy resulted in 92.7% maternal survival and 56.0% healthy live births, with emergency surgery significantly correlating with worse maternal prognosis (P<0.001).
Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context: