Key result
Chronic alcohol consumption was associated with a diminished adrenocortical response to surgical stress, which was not altered by pre-operative alcohol infusion.
Why the study?
Does pre-operative alcohol infusion alter the adrenocortical response to surgical stress in chronic alcoholic patients?
Population
53 surgical patients
Comparison
Pre-operative infusion of alcohol vs Non-alcoholics and/or alcoholics without…
Design
Cohort
Authors
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May warrant perioperative vigilance for blunted stress response in chronic drinkers; leaves open causal confirmation and infusion effects in prospective trials.
Observational (n=53)
Does pre-operative alcohol infusion alter the adrenocortical response to surgical stress in chronic alcoholic patients?
Chronic alcohol consumption diminishes the adrenocortical response to surgical stress, an effect that is not reversed by pre-operative alcohol infusion despite the suppression of withdrawal symptoms.
Haxholdt et al. (1982) conducted an observational in Operative trauma (n=53). Chronic alcohol consumption vs. Non-alcoholics was evaluated on Adrenocortical response to surgical stress. Chronic alcohol consumption was associated with a diminished adrenocortical response to surgical stress, which was not altered by pre-operative alcohol infusion.
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