In February 1973, scombroid fish poisoning occurred in 232 persons who had eaten from either of two lots of commercially canned tuna. Cases occurred in four states, with no reported hospitalizations or deaths. Patients became ill about 45 minutes after eating the fish; symptoms lasted about eight hours. Contaminated fish contained histamine levels of 68 to 280 mg/100 gm of fish muscle. (JAMA228:1268-1269, 1974)
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Michael Merson (1974) studied this question.
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