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For a better understanding of various dermatoses, it is imperative for any physician practising dermatology to have a good theoretical knowledge of the underlying pathophysiologic processes involved in various systemic diseases involving the skin. For an easy grasp over this topic, we have discussed the various phenomena under three broad categories, like (a) clinical--Meyerson, Meirowsky, pathergy, Renbok, (b) laboratory--LE cell, prozone and (c) histopathology--Splendore-Hoeppli.
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Khopkar et al. (2011) studied this question.
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