Key result
The provided abstract is truncated and reports no quantitative findings regarding the effect of hypotension on cerebral arteriole sensitivity.
No quantitative findings reported; leaves open hypotension effects on cerebral arteriole sensitivity.
CONSTRICTION of cerebral arterioles has recently been observed over areas of experimental infarction.1,2The mechanism of this constriction is not understood, but it has been stated that the segmental constriction illustrated in these reports2does not resemble passive collapse due to reduced perfusion pressure.1Instead, it has been suggested that some chemical agent is released from the ischemic tissue, and that this hypothetical substance produces the constriction observed.1Since perfusion pressure is reduced in the area of infarction, it occurred to us that at least one other factor might account for the vasoconstriction beside the regional release of a vasoconstrictor. This factor would be an increased sensitivity of the vessels to a constricting influence. Although many publications have been written about the effect of altered pressure on vascular diameter3,4and about the effects of chronic hypertension on cerebrovascular reactivity,4we could find no
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William I. Rosenblum (1970) studied Cerebral infarction. Hypotension was evaluated. The provided abstract is truncated and reports no quantitative findings regarding the effect of hypotension on cerebral arteriole sensitivity.
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