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An unsaturated fatty acid preparation containing 90 to 95% linoleic acid was tested on cholesterol-induced hypercholesterolemia and atherosclerosis in the rabbit. The rabbits, treated with cholesterol dissolved in the unsaturated fatty acid, revealed a significantly higher hypercholesterolemia and more marked atherosclerosis than the rabbits that were treated with cholesterol dissolved in the same amount of olive oil.
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Roña et al. (1959) studied this question.
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