Ca2+ Channels and Peptide Release From Neurosecretory Terminals

Evoked release of neuropeptides and/or neurotransmitters requires activation of membrane Ca2+ channels. Because of the generally small size and inaccessibility of nerve endings, most electrophysiological studies have observed this activation only in cell bodies. However, recent techniques have permitted insights into the diversity and behavior of Ca2+ channels in neurosecretory terminals.