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October 22, 2011Journal of Biological ChemistryOpen Access

MUC1 Protein Expression in Tumor Cells Regulates Transcription of Proinflammatory Cytokines by Forming a Complex with Nuclear Factor-κB p65 and Binding to Cytokine Promoters

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Authors

SCSandra CascioUniversity of PittsburghLZLixin ZhangShihezi UniversityOFOlivera J. FinnUniversity of Pittsburgh

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Cascio et al. (2011) studied this question.

synapsesocial.com/papers/6a93e5729fbe5f86ceb94279https://doi.org/10.1074/jbc.m111.297630
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Also Consider

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  1. 1Kappa B-Specific DNA Binding Proteins: Role in the Regulation of Human Interleukin-2 Gene Expression1989 · 324 citations
  2. 2Interaction of NF-κB and NFAT with the Interferon-γ Promoter1997 · 436 citations
  3. 3MUC1 Oncoprotein Blocks Glycogen Synthase Kinase 3β–Mediated Phosphorylation and Degradation of β-Catenin2005 · 231 citations
  4. 4MUC1-C Oncoprotein Functions as a Direct Activator of the Nuclear Factor-κB p65 Transcription Factor2009 · 191 citations