Comparative analysis reveals aberrant brain network organization in early-onset schizophrenia, suggesting distinct neurodevelopmental disruption compared to adult-onset forms.
are included in developmental monitoring resources from the US Centers for Disease Control and Prevention's Learn the Signs Act Early program and the American Academy of Pediatrics' Bright Futures guidelines."Because children with autism and other DD are likely to struggle with daily skills in adolescence, any way to identify them early to provide support to promote independence would be helpful, the researchers wrote."Future investigations are needed to explore whether services and supports to boost expressive language and fine motor skills and reduce attention problems in children with autism and other DD can improve acquisition of DLS and promote greater independence in adolescence." LimitationsThe researchers detailed the following limitations: • Reliance on a caregiver-reported measure of DLS, which may underestimate functional performance.• The study was unable to examine other contextual factors, such as the opportunity to learn or perform a skill, which may influence independence.For instance, adolescents may not be expected to run errands until they obtain a driver's license or learn to use public transportation.• The racial and ethnic distribution of the current sample was predominately non-Hispanic White and differed from that of nonresponders.This raises the possibility of selection bias, and findings should be interpreted with caution until replicated in more diverse samples. Research briefsEarly onset schizophrenia may have aberrant brain network compared to adult-onset schizophrenia
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Alison Knopf (2026) studied this question.
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