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Epidemiological analysis estimates substantial under-detection of human rabies in the United States, indicating only seven percent of deaths were confirmed between 2000 and 2024.
Based on multiple instances of human-to-human rabies transmission via organ or tissue transplantation from initially undiagnosed rabies-infected donors, we estimate 856 (213–2220) human rabies deaths in the United States (US) from 2000 to 2024, meaning that only around 7% of human rabies deaths in the US were confirmed during this period.
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Kim et al. (2026) studied this question.
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