The synthesis of thiazolo[4,5‐d]pyridazines and the unknown ring systems, thiazolo[4,5‐d]‐1,2,4‐triazolo‐ and tetrazolo[4,3‐b]pyridazines as well as thiazolo(4,5‐d]pyridazino[2,3‐c]2H triazines, has been achieved according to different pathways. Biological testing of the new tricyclic heterocycles revealed that some of these compounds possess remarkable antibacterial activity.
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Makki et al. (1996) studied this question.
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