A case of Bowen's disease with invasive adnexal carcinoma.

This is the authors' abstract. We don't add key points for this paper.

A-66-year old worman had noticed a pigmented lesion on the lateral side of the right lower leg for several years. The part of the lesion began to elevate 1 year previously. The physical examination revealed a coin size brown, keratotic plaque which had a reddish nodule at the upper portion of the lesion. Histopathology revealed an apparent picture of Bowen's disease in the pigmented lesion, while there was continuously adnexal carcinoma in the nodule. Immunohistochemically, this Bowen's disease and the adnexal carcinoma showed respective different antigenecities.Whereas Bowen's disease is generally regarded as a premalignant dermatosis, 3% to 5% of patients may develope invasive carcinomas if untreated. The case like the patient case of Bowen's disease combined with other adnexal carcinoma is very rare. For the present case, Bowen's disease with invasive adnexal carcinoma was diagnosed. [Skin Cancer (Japan) 2000; 15 :155-158]