Key result
During pulmonary artery thromboendarterectomy, PGE1 infusion caused more marked decreases in mean arterial pressure and systemic vascular resistance than in mean pulmonary artery pressure and pulmonary vascular resistance.
Case Report (n=2)
No
During pulmonary thromboendarterectomy, pulmonary artery occlusion can cause acute right ventricular failure, and PGE1 infusion may dangerously lower systemic blood pressure without reducing pulmonary vascular resistance.
PGE1 may cause disproportionate systemic hypotension during thromboendarterectomy; single case report leaves open its pulmonary selectivity.
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Oka et al. (1995) conducted a case report in Chronic pulmonary thromboembolism (n=2). Pulmonary artery thromboendarterectomy and PGE1 infusion vs. Baseline/intraoperative states was evaluated on Hemodynamic changes (right ventricular functions, BP, CI, SVI). During pulmonary artery thromboendarterectomy, PGE1 infusion caused more marked decreases in mean arterial pressure and systemic vascular resistance than in mean pulmonary artery pressure and pulmonary vascular resistance.
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