Immunologic and cytologic tests indicate that the thymuses of lethally irradiated mice protected with rat bone marrow are repopulated by rat-type cells. The agglutination tests showed this repopulation of the thymus by donor cells to be 100% complete 30 days after treatment, and the cytologic analysis of dividing cells showed 100% rat-type cells 21 days after treatment. Although the histologic architecture of these thymuses was often normal, recovery of the thymuses in terms of weight was incomplete.
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Gengozian et al. (1957) studied this question.