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A system is described which rapidly detects antibody‐mediated cell‐dependent immunity in multiparous women; their purified peripheral lymphocytes act as effector cells against 51Cr lymphocytes as targets, in the presence of specific antibody. Added complement was not required. The antibody can be detected in plasma, serum, and IgG preparations. The specific site of action of the antibody is primarily the target cell. Normal lymphocytes can be converted into effector cells. Antibodies demonstrated partial HL–A specificity and a high degree of sensitivity.
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McConnachie et al. (1973) studied this question.
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