Key result
Surgery was required to treat recurrent cardioembolic strokes in a 43-year-old man with a prior Mustard procedure, caused by a calcified, fractured, and thrombosed baffle resistant to anticoagulation.
Why the study?
Thromboembolic events from baffle leaks after atrial switch operations are well known, but thrombosis at the pulmonary venous baffle as a source of cardioembolic stroke had not been previously reported.
Case Report (n=1)
Thrombosis at the pulmonary venous baffle due to a calcified and fractured Mustard patch can be a source of recurrent cardioembolic strokes requiring surgical intervention.
Background: After an atrial switch operation, baffle complications such as stenosis and dehiscence are common. While thromboembolic events attributed to baffle leaks are well known, thrombosis at the pulmonary venous baffle as a source of cardioembolic stroke has not been previously reported. Case summary: We describe the case of a 43-year-old Caucasian male with recurrent cardioembolic strokes due to a calcified, broken, and thrombosed baffle with floaty, anticoagulant-resistant thrombi adhered to the side of the pulmonary venous return of Mustard patch. Surgery was the only curative option due to thrombi recurrence under different regimes of anticoagulation. Discussion: A case of recurrent cardioembolic strokes long after Mustard surgery due to thrombi on a heavily calcified pericardial patch is presented. A fracture in the patch led to the exposure of thrombogenic material, which had accumulated around the pacemaker (PM) leads on the systemic venous side of the baffle. This exposure allowed thrombotic material to reach the pulmonary venous side, ultimately entering the subaortic right ventricle and the systemic circulation. In the Mustard procedure, the material used for the baffle construction is prone to degeneration and calcification over time. We hypothesize that chronic mechanical stress from the PM leads might have contributed to the gradual erosion and fracture and consequently thrombosis of the heavily calcified patch, leading to recurrent strokes. Surgery became necessary as aggressive anticoagulation failed to prevent thrombus recurrence.
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Ruperti‐Repilado et al. (2025) conducted a case report in Recurrent cardioembolic strokes in dextro-transposition of the great arteries corrected by atrial switch (n=1). Surgery was evaluated. Surgery was required to treat recurrent cardioembolic strokes in a 43-year-old man with a prior Mustard procedure, caused by a calcified, fractured, and thrombosed baffle resistant to anticoagulation.
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