Key result
Preoperative mental health conditions are linked to ~6.8-fold higher odds of suicidal ideation after bariatric surgery.
Why the study?
It was unknown whether documented preoperative mental health conditions were associated with early postoperative psychiatric events and metabolic outcomes after primary metabolic-bariatric surgery.
Are documented preoperative mental health conditions associated with early postoperative psychiatric events and metabolic outcomes after primary metabolic-bariatric surgery?
Cohort (n=482)
No
Are documented preoperative mental health conditions associated with early postoperative psychiatric events and metabolic outcomes after primary metabolic-bariatric surgery?
Odds Ratio: 6.75 (95% CI 1.09–41.86)
Absolute Event Rate: 2.8% vs 0.4%
p-value: p=0.0420
Patients with preoperative mental health conditions undergoing metabolic-bariatric surgery achieve comparable metabolic benefits but have a higher risk of early suicidality-related events, highlighting the need for structured postoperative mental health follow-up.
Preoperative MH conditions may link to early psychiatric events after MBS; leaves open effects on metabolic outcomes and needs prospective confirmation.
Objective To evaluate whether documented preoperative mental health (MH) conditions were associated with early postoperative psychiatric events and metabolic outcomes after primary metabolic-bariatric surgery (MBS). Methods A retrospective cohort study of adults who underwent primary MBS at a tertiary UK bariatric centre between April 2021 and March 2024 was conducted. Preoperative MH conditions and postoperative outcomes were identified via review of electronic health records. Comparisons between groups were analysed using Fisher’s exact test and regression models adjusted for age, sex, preoperative BMI, and surgery type. Results Among 482 patients, 217 (45.0%) had at least one documented preoperative MH condition. During 2-year follow-up, suicidal ideation was recorded in 6/217 (2.8%) in the MH group versus 1/265 (0.4%) in the non-MH group and self-harm (including suicide attempt) in 5/217 (2.3%) versus 1/265 (0.4%), respectively. Preoperative MH conditions were associated with higher odds of postoperative suicidal ideation (OR 6.75, 95% CI 1.09–41.86; p = 0.0420), while the association with self-harm was directionally similar but not statistically significant (OR 5.10, 95% CI 0.80–32.72; p = 0.0860). Weight-loss and metabolic outcomes did not differ materially by baseline MH status. Conclusions In this single-centre cohort, patients with documented preoperative MH conditions achieved comparable metabolic benefit after surgery but had higher recorded early suicidality-related events. Although causality cannot be inferred, these findings support structured postoperative MH follow-up.
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Ortega et al. (2026) conducted a cohort in Obesity (n=482). Preoperative mental health condition vs. No preoperative mental health condition was evaluated on Postoperative suicidal ideation (OR 6.75, 95% CI 1.09-41.86, p=0.0420). Preoperative mental health conditions were associated with a 6.75-fold higher odds of postoperative suicidal ideation at 2 years following metabolic-bariatric surgery.
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